Water → HCID 14645390, compound

HRID 727965Notes

Reaction equation

HRID 727965 reaction equation
[OH:1][CH:2]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])[CH2:3][C:4]([OH:6])=[O:5].N1C=CC=CC=1.[C:19](OC(=O)C)(=[O:21])[CH3:20].O>Cl>[C:19]([O:1][CH:2]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])[CH2:3][C:4]([OH:6])=[O:5])(=[O:21])[CH3:20]

Participants

6

Reactant 4

HCID 962WaterHCID 1049PyridineHCID 7918Acetic AnhydrideHCID 365993-Hydroxynonanoic acid

Product 1

HCID 14645390HCID 14645390, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

Then 5.0 g of this β-hydroxynonanoic acid was mixed with 20 ml of anhydrous pyridine and 3.2 ml of acetic anhydride under ice cooling, and the mixture was stirred at room temperature overnight and cooled with ice. Then, 5 ml of distilled water was added to the mixture, the mixture was dissolved in 1N hydrochloric acid, and the solution was extracted with ether. The ether layer was washed with a saturated aqueous sodium chloride solution and dehydrated on magnesium sulfate. Then, the ether was evaporated and the residue was concentrated to obtain 5.4 g of β-acetoxynonanoic acid.

Workup

  1. temperaturecooled with ice
  2. extractionthe solution was extracted with ether
  3. washThe ether layer was washed with a saturated aqueous sodium chloride solution
  4. customThen, the ether was evaporated
  5. concentrationthe residue was concentrated

Sources & evidence

ORD record
ord-ccaf12b03fff4b3cabbda9c4c4e7827b
Source dataset
uspto-grants-1991_09
Patent number
US05045228

Reaction notes

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