Water → [1,1'-Biphenyl]-4-ol, 4'-(decyloxy)-

In 25 ml of methanol was dissolved 5.0 g of biphenyl, and a solution comprising 1.3 g of sodium hydroxide, 1 ml of water and 5 ml of methanol was added to the above solution. The mixture was refluxed under heating, a solution of 5.4 g of n-bromodecane in 5 ml of methanol was dropped into the formed solution, and the mixture was refluxed overnight. The reaction liquid was concentrated under a reduced pressure and the pH value was adjusted to 2 to 3 by water and hydrochloric acid. The mixture was extracted three times with chloroform, and the extract layer was washed with a saturated aqueous sodium chloride solution dried on magnesium sulfate, concentrated under a reduced pressure and purified by 4-hydroxy-4'-decyloxybiphenyl.

1. additionwas added to the above solution
2. temperatureThe mixture was refluxed
3. temperatureunder heating
4. temperaturethe mixture was refluxed overnight
5. customThe reaction liquid
6. concentrationwas concentrated under a reduced pressure
7. extractionThe mixture was extracted three times with chloroform
8. washthe extract layer was washed with a saturated aqueous sodium chloride solution
9. customdried on magnesium sulfate
10. concentrationconcentrated under a reduced pressure
11. custompurified by 4-hydroxy-4'-decyloxybiphenyl

ORD record

ord-aa314a1e77e94eed825daa28305c4f69

Source dataset

uspto-grants-1991_09

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US05045228