反应详情

100 g of 5-cyano-2,4,6-triiodoisophthalic acid is suspended in 400 ml of water and dissolved by adding 20 g of sodium hydroxide. The solution is maintained at +60° C. for 3 hours, then poured under agitation into 60 ml of concentrated hydrochloric acid. After several hours of stirring in an ice bath, the precipitate is vacuum-filtered, washed with a small amount of ice-cooled water, and dried at 50° C., thus obtaining 98 g (=95% of theory) or 5-carbamoyl-2,4,6-triiodoisophthalic acid having a decomposition point of above 280° C., as a white powder.

1. dissolutiondissolved
2. temperatureThe solution is maintained at +60° C. for 3 hours
3. filtrationthe precipitate is vacuum-filtered
4. washwashed with a small amount of ice-
5. temperaturecooled water
6. customdried at 50° C.