Hydrochloric Acid → HCID 19823553, compound

HRID 728050Notes

Reaction equation

HRID 728050 reaction equation
[ClH:1].Cl.[OH:3][CH:4]([CH2:26][O:27][C:28]1[CH:33]=[CH:32][C:31]([O:34]CC2C=CC=CC=2)=[CH:30][CH:29]=1)[CH2:5][NH:6][C:7]([CH3:25])([CH3:24])[CH2:8][N:9]([CH:11]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH3:10].Cl>C(O)C>[ClH:1].[ClH:1].[OH:3][CH:4]([CH2:26][O:27][C:28]1[CH:29]=[CH:30][C:31]([OH:34])=[CH:32][CH:33]=1)[CH2:5][NH:6][C:7]([CH3:25])([CH3:24])[CH2:8][N:9]([CH:11]([C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH3:10]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19823572HCID 19823572, compound

Product 1

HCID 19823553HCID 19823553, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of b 2-[2-hydroxy-3-(4-phenylmethoxyphenoxy)-propylamino]-2-methyl-N-diphenylmethyl-N-methyl-propylamine dihydrochloride (5 g; 0.0084 mol), prepared as described in Example 10, in ethyl alcohol saturated with hydrochloric acid (50 ml) is refluxed for 6 hours.

Workup

  1. temperatureis refluxed for 6 hours

Sources & evidence

ORD record
ord-c713fc18016341c39f855cfc5efa7dbd
Source dataset
uspto-grants-1991_09
Patent number
US05047425

Reaction notes

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