Hydrochloric Acid → HCID 10594810, compound

Participants

Reaction Steps

To a solution of ethyl 3-(2,4-dibenzyloxyphenyl)propionate (12.0 g) in ethanol (300 ml), sodium hydroxide (10.3 g) was added, followed by stirring at room temperature for 6 hours. The reaction mixture was adjusted to pH 4.0 with addition of 5N hydrochloric acid solution. Ethanol was distilled off and to the residue was added water. The precipitated crystal was collected by filtration, washed with water and dried to obtain as colorless crystal 3-(2,4-dibenzyloxyphenyl)propionic acid (9.4 g).

Provenance & Evidence