Methyl isothiocyanate → HCID 9970424, compound

Participants

Reaction Steps

A solution of 2-[2-(4-aminophenyl)ethyl]pyridine (5.8 g) and methyl isothiocyanate (2.6 g) in ethanol (60 ml) was refluxed for one hour. The reaction mixture was evaporated in vacuo to give a crystalline residue, which was recrystallized from a mixture of ethyl acetate and diisopropyl ether to give 2-[2-{4-(3-methylthioureido)phenyl}ethyl]pyridine (7.3 g).

Provenance & Evidence