Sodium Hydroxide → HCID 15684679, compound

Participants

Reaction Steps

A mixture of S-(7-methylimidazo[1,2-a]pyridin-2-ylmethyl)isothiourea hydrochloride (7.7 g) and sodium hydroxide (1.2 g) in water (54 ml) was refluxed for 2 hours and the reaction mixture was extracted with ethyl acetate. The extract was washed with water, and dried over magnesium sulfate. The solvent was evaporated in vacuo to give 7-methylimidazo[1,2-a]pyridin-2-ylmethanethiol (4.2 g).

Provenance & Evidence