Sodium Hydroxide → HCID 53634746, compound

HRID 728191Notes

Reaction equation

HRID 728191 reaction equation
C([NH:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]=[CH:12][C:13]2[N:14]=[CH:15][N:16]([C:19]([C:32]3[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=3)([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)[C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:17]=2[CH3:18])=[CH:7][C:6]=1[N+:38]([O-:40])=[O:39])(=O)C.[OH-].[Na+]>C(O)C>[NH2:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]=[CH:12][C:13]2[N:14]=[CH:15][N:16]([C:19]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)([C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=3)[C:32]3[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=3)[C:17]=2[CH3:18])=[CH:7][C:6]=1[N+:38]([O-:40])=[O:39]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 53910051HCID 53910051, compound

Product 1

HCID 53634746HCID 53634746, compoundYield 48.6%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 4-[2-(4-acetamido-3-nitrophenyl)vinyl]-5-methyl-1-tritylimidazole (6.3 g) in ethanol (60 ml) and 1N-sodium hydroxide (23.8 ml) was refluxed for 1 hour and the mixture was cooled. The isolated precipitate was collected by filtration and the precipitate was washed with aqueous ethanol to give 4-[2-(4-amino-3-nitrophenyl)vinyl]-5-methyl-1-tritylimidazole (2.82 g).

Workup

  1. temperaturewas refluxed for 1 hour
  2. temperaturethe mixture was cooled
  3. filtrationThe isolated precipitate was collected by filtration
  4. washthe precipitate was washed with aqueous ethanol

Sources & evidence

ORD record
ord-a078c8d164ce4716bcd99b67fe9c0f5b
Source dataset
uspto-grants-1991_09
Patent number
US05047411

Reaction notes

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