12-Aminododecanoic Acid → HCID 19824103, compound

HRID 728237Notes

Reaction equation

HRID 728237 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14]>CO>[O:14]=[C:13]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH3:3]

Participants

3

Reactant 1

HCID 6966112-Aminododecanoic Acid

Product 1

HCID 19824103HCID 19824103, compoundYield 110.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Reaction similar to example 2, of 9.30 g (50.0 mmol) N-hydroxysuccinimide and 12.0 g (58.0 mmol) DCC gave 14.0 g (100%) of the succinimidylester, which was reacted with 12.5 g (58.1 mmol) 12-aminododecanoic acid to yield 12.3 g (65%) colourless crystals, m.p. 102°-104° C. (methanol).

Sources & evidence

ORD record
ord-f9d2fbab8a39468b8883567d49bd7737
Source dataset
uspto-grants-1991_09
Patent number
US05047535

Reaction notes

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