HRID728507

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8471

Triethylamine

C6H15N

HCID31297

Methanesulfonyl chloride

CH3ClO2S

结构：CCCCCCCCCCCCCCCCSCC(CO)CC(C)OC(=O)c1ccccc1

HCID14834992

未命名化合物

结构：CCCCCCCCCCCCCCCCSCC(CN=[N+]=[N-])NC(=O)OC

HCID14835094

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCSCC(COS(C)(=O)=O)CC(C)OC(=O)c1ccccc1

HCID53635267

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

A mixture of 1.268 g (2.65 mM) of 2-(2-benzoyloxypropan-1-yl)-3-n-hexadecylthiopropanol m12, 0.270 ml (3.45 mM) of methanesulfonyl chloride and 0.56 ml (3.98 mM) of triethylamine in 30 ml of dichloromethane is allowed to react by the same procedure as described in (52) and the crude product of the titled compound m12a is obtained.

WORKUP

后处理

customto react by the same procedure

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-38b9091d7344456e8154a5a4554ff15b
来源数据集: uspto-grants-1991_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05047540
来源说明: uspto-grants-1991_09

反应 SMILES

[C:1]([O:9][CH:10]([CH3:33])[CH2:11][CH:12]([CH2:15][S:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH2:13][OH:14])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:34][S:35](Cl)(=[O:37])=[O:36].C(N(CC)CC)C.N(CC(NC(OC)=O)CSCCCCCCCCCCCCCCCC)=[N+]=[N-]>ClCCl>[CH3:34][S:35]([O:14][CH2:13][CH:12]([CH2:11][CH:10]([O:9][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH3:33])[CH2:15][S:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])(=[O:37])=[O:36]