4-Thiazoleacetic acid, 2-amino-alpha-oxo- → HCID 88527855, compound

Participants

Reaction Steps

N.m.r. in solvent B: 4.73 (q, 2H), 6.93 (s, 1H). 15. The method of condensation was that described in Footnote 11. 16. N.m.r. in solvent B: 3.5 (d, 1H), 3.75 (d, 1H), 3.95 (d, 1H), 4.5 (d, 1H), 4.75 (d, 1H), 4.95 (d, 1H), 5.3 (d, 1H), 5.9 (d, 1H), 7.2 (s, 1H). 17. The starting material was prepared by reaction of O-(1-methylimidazol-2-yl)methylhydroxylamine with 2-(2-aminothiazol-4-yl)glyoxylic acid to give 2-(2-aminothiazol-4-yl)-2-[(Z)-(1-methylimidazol-2-yl)-methoxy-imino]acetic acid.

Provenance & Evidence