Levemopamil → HCID 11771582, compound

Participants

Reaction Steps

A solution of 17 g (50 mmol) of (S)-2-isopropyl-5-(methylphenethylamino)-2-phenylvaleronitrile in 50 ml of dichloromethane was added dropwise, at 0° C., to a solution of 6 ml (66 mmol) of vinyl chloroformate in 30 ml of dichloromethane. The temperature was then allowed to increase to room temperature, and the mixture was heated for 1 hour at 80° C.

Provenance & Evidence