Phenyl glycidyl ether → HCID 53680309, compound

Participants

Reaction Steps

To a solution of 7.95 9 (20 mmol) N-[2-(phenylmethyl)amino)ethyl]-N-propyl-4-[(methylsulfonyl)amino]benzamide in 20 mL 10% aqueous methanol is added 2.89 mL (21 mmol) 1,2-epoxy-3-phenoxypropane. The solution is stirred at room temperature for 24 h. After this time, the solvents are evaporated and the title compound is obtained as a foamy solid via column chromatography on silica gel (hexane:acetone, 9:1).

Provenance & Evidence