HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphoric Acid → HCID 67689897, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphoric Acid | HCID 1004 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | ((p-(2-Methoxyethyl)phenoxy)methyl)oxirane | HCID 92515 | — |
| Reactant | 1-[4-[(Methylsulfonyl)amino]benzoyl]piperazine hydrochloride | HCID 67938782 | — |
| Product | HCID 67689897 | HCID 67689897 | — |
Reaction Steps
Add 2.64 g (.013 mol) of 1,2-epoxy-3-[4-(2-methoxyethyl)phenoxy]propane to a solution of 3.86 (12 mmol) 1-[4-[(methylsulfonyl)amino]benzoyl]piperazine hydrochloride in 50 mL MeOHand 13 mL 1 N NaOH. Heat the resultant solution at 50° C. for about 24 h. Cool the solution to room temperature and evaporate the solvents. Dissolve the resultant oil in ethanol and acidify with one equivalent of phosphoric acid. Remove the solvents to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05051423 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-6572aa27bc024775a1289fd258b75283 |
| Source note | uspto-grants-1991_09 |