HCID 21667292, compound → HCID 86745085, compound

HRID 728855Notes

Reaction equation

HRID 728855 reaction equation
C([O:3][C:4](=[O:21])[CH:5]([NH:18]C=O)/[C:6](/[CH3:17])=[CH:7]/[CH2:8][P:9]([O:14]CC)([O:11]CC)=[O:10])C>Cl>[NH2:18][CH:5](/[C:6](/[CH3:17])=[CH:7]/[CH2:8][P:9]([OH:14])([OH:11])=[O:10])[C:4]([OH:21])=[O:3]

Participants

3

Reactant 1

HCID 21667292HCID 21667292, compound

Product 1

HCID 86745085HCID 86745085, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

6.3 g of E-2-formylamino-3-methyl-5-diethylphosphono-3-pentenoic acid ethylester are heated for 30 hours at 100°-100° under nitrogen in 400 ml of 4.35N hydrochloric acid. Working up as in Example 11 yields E-2-amino-3-methyl-5-phosphono-3-pentenoic acid in the form of a white powder, m.p. 168°, 1H-NMR (D2O): 1.50 (d, 3H, CH3); 2.4 (m, 2H, CH2); 4.30 (s, 1H, C(2)--H); 5.60 (m, 1H, C(4)--H).

Sources & evidence

ORD record
ord-0a6c2dc481df41fa9ae733d46f1f2b82
Source dataset
uspto-grants-1991_09
Patent number
US05051413

Reaction notes

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