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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 728912Generated: November 1, 2026

4-Benzyl-2-cyano-1-phenylpiperazine → 1-Phenyl-4-(phenylmethyl)-2-piperazinemethanamine

https://huagongshe.com/reaction/728912

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Benzyl-2-cyano-1-phenylpiperazineHCID 14998752—
ReactantAluminium lithium hydrideHCID 21226445—
Product1-Phenyl-4-(phenylmethyl)-2-piperazinemethanamineHCID 14998770—

Reaction Steps

In a manner similar to Preparation 2, react 1-phenyl-4-(phenylmethyl)-2-piperazinecarbonitrile (16.6 g, 60 mmol) with lithium aluminum hydride (6.8 g, 180 mmol) to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05051422
Source datasetuspto-grants-1991_09
ORD IDord-347d02fb057a4f46b75e25381f1c3c18
Source noteuspto-grants-1991_09