HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[(Methylsulfonyl)amino]benzoyl chloride → N-[[4-(2-Methoxyphenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]4-[(methylsulfonyl)amino]benzamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[(Methylsulfonyl)amino]benzoyl chloride | HCID 11791119 | — |
| Reactant | 4-(2-Methoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamine | HCID 14998772 | — |
| Product | N-[[4-(2-Methoxyphenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]4-[(methylsulfonyl)amino]benzamide hydrochloride | HCID 19755013 | — |
Reaction Steps
In a manner similar to Preparation 3, react 4-(2-methoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamine (3.8 g, 12 mmol) with 4-[(methylsulfonyl)amino]benzoyl chloride (3.2 g, 14 mmol) to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05051422 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-27f9fd67ab0c4e4385f7a9419393a2b2 |
| Source note | uspto-grants-1991_09 |