Stannous chloride dihydrate → HCID 14998809, compound

HRID 728927Notes

Reaction equation

HRID 728927 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11]([CH:13]2[CH2:18][N:17]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:16][CH2:15][N:14]2[CH2:25][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)=[O:12])=[CH:6][CH:5]=1)([O-])=O.O.O.[Sn](Cl)Cl>>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([NH:10][C:11]([CH:13]2[CH2:18][N:17]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:16][CH2:15][N:14]2[CH2:25][C:26]2[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=2)=[O:12])=[CH:8][CH:9]=1

Participants

3

Reactant 2

HCID 61436Stannous chloride dihydrateHCID 14998807HCID 14998807, compound

Product 1

HCID 14998809HCID 14998809, compound

Procedure

In a manner similar to Preparation 20, react N-(4-nitrophenyl)-4-phenyl-1-(phenylmethyl)-2-piperazinecarboxamide (6.85 g, 16.8 mmol) with tin (II) chloride dihydrate (18.5 g, 82 mmol) to obtainthe title compound.

Workup

  1. customIn a manner similar to Preparation 20

Sources & evidence

ORD record
ord-6c10905a260b4137aee892c42392e0e5
Source dataset
uspto-grants-1991_09
Patent number
US05051422

Reaction notes

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