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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 728929Generated: October 27, 2026

2,3-Dibromopropionamide → 4-[3-(Acetylamino)phenyl]-1-(phenylmethyl)-2-piperazinecarboxamide

https://huagongshe.com/reaction/728929

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DibromopropionamideHCID 85798—
ReactantN-[3-[[2-[(phenylmethyl)amino]ethyl]amino]phenyl]acetamideHCID 14998757—
Product4-[3-(Acetylamino)phenyl]-1-(phenylmethyl)-2-piperazinecarboxamideHCID 14998758—

Reaction Steps

In a manner similar to Preparation 1, react N-[3-[[2-[(phenylmethyl)amino]ethyl]amino]phenyl]acetamide (25.6 g, 90.4 mmol) with 2,3-dibromopropanamide (41.8 g, 180.8 mmol) to obtain the titlecompound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05051422
Source datasetuspto-grants-1991_09
ORD IDord-8bb2b618831245f59fdde9b22b1dd593
Source noteuspto-grants-1991_09