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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 728942Generated: November 1, 2026

4-(3-Aminophenyl)-2-piperazinemethanol → 1-(3-Aminophenyl)-3-[[[4-(2-methyl-1H-imidazol-1-yl)phenyl]methoxy]methyl]piperazine

https://huagongshe.com/reaction/728942

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Aminophenyl)-2-piperazinemethanolHCID 14998820—
Reactant1-(4-Chloromethylphenyl)-2-methyl-1H-imidazoleHCID 14998821—
Product1-(3-Aminophenyl)-3-[[[4-(2-methyl-1H-imidazol-1-yl)phenyl]methoxy]methyl]piperazineHCID 14998822—

Reaction Steps

In a manner similar to Preparation 19, react 4-(3-aminophenyl)-2-piperazinemethanol with 1-[4-(chloromethyl)phenyl]-2-methyl-1H-imidazole to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05051422
Source datasetuspto-grants-1991_09
ORD IDord-8644a1e1f5b04ee09a05d9439918af71
Source noteuspto-grants-1991_09