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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 728950Generated: October 31, 2026

4-(3,5-Dimethoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamine → N-[[4-(3,5-Dimethoxyphenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]-4-[(ethylsulfonyl)amino]benzenesulfonamide

https://huagongshe.com/reaction/728950

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3,5-Dimethoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamineHCID 14998774—
Reactant4-[(Ethylsulfonyl)amino]benzenesulfonyl chlorideHCID 14998792—
ProductN-[[4-(3,5-Dimethoxyphenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]-4-[(ethylsulfonyl)amino]benzenesulfonamideHCID 14998793—

Reaction Steps

In a manner similar to Preparation 3, react 4-(3,5-dimethoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamine with 4-[(ethylsulfonyl)amino]benzenesulfonyl chloride to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05051422
Source datasetuspto-grants-1991_09
ORD IDord-22c56e0638a7403fa033ba921fbc650d
Source noteuspto-grants-1991_09