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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 728981Generated: October 31, 2026

N-[[4-(2-Methoxyphenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]4-[(methylsulfonyl)amino]benzamide hydrochloride → N-[[4-(2-Methoxyphenyl)piperazin-2-yl]methyl]-4-[(methylsulfonyl)amino]benzamide hydrochloride

https://huagongshe.com/reaction/728981

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-[[4-(2-Methoxyphenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]4-[(methylsulfonyl)amino]benzamide hydrochlorideHCID 19755013—
CatalystPalladium hydroxideHCID 9942167—
ProductN-[[4-(2-Methoxyphenyl)piperazin-2-yl]methyl]-4-[(methylsulfonyl)amino]benzamide hydrochlorideHCID 67902867—

Reaction Steps

In a manner similar to Example 1, react N-[[4-(2-methoxyphenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]-4-[(methylsulfonyl)amino]benzamide hydrochloride (8.7 g, 16 mmol) with H2 over Pd(OH)2 (0.2 g) catalyst to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05051422
Source datasetuspto-grants-1991_09
ORD IDord-875576f4b0cd4b80b36aea1b811ab3ac
Source noteuspto-grants-1991_09