HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → N-[[4-(3-Chlorophenyl)piperazin-2-yl]methyl]-N-(1-methylethyl)-4-[(methylsulfonyl)amino]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | HCID 19755015 | HCID 19755015 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | N-[[4-(3-Chlorophenyl)piperazin-2-yl]methyl]-N-(1-methylethyl)-4-[(methylsulfonyl)amino]benzamide | HCID 14998862 | — |
Reaction Steps
In a manner similar to Example 11, react N-[[4-(3-chlorophenyl)-1-[(3,4-dimethoxyphenyl)methyl]piperazin-2-yl]methyl]-N-(1-methylethyl)-4-[(methylsulfonyl)amino]benzamide with methoxybenzeneand a 5% solution of concentrated H2SO4 in trifluoroacetic acid to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05051422 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-82ae2b940737441a85eb2c14358ced5b |
| Source note | uspto-grants-1991_09 |