HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → ethyl N-[3-(2-allyl-4-carbamoylmethylphenoxy)-2-hydroxypropyl]-3-aminopropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 3-aminopropanoate | HCID 419889 | — |
| Reactant | HCID 54437989 | HCID 54437989 | — |
| Product | ethyl N-[3-(2-allyl-4-carbamoylmethylphenoxy)-2-hydroxypropyl]-3-aminopropanoate | HCID 67929459 | — |
Reaction Steps
This compound was prepared in accordance with Example 1 using 10.8 g of thehydrochloride of ethyl 3-aminopropanoate, 11.6 g of 3-allyl-4-(2,3-epoxypropoxy)phenylacetamide, and 2.84 g NaOH. The crude product was crystallized from ethyl acetate. Yield 1.7 g. Melting point 98° C. (base). The structure was determined using NMR and equivalent weight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05051446 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-853cc4b8ba6142f9b54d72c0f1ad1eef |
| Source note | uspto-grants-1991_09 |