HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 54523481, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-(Oxiran-2-ylmethoxy)benzonitrile | HCID 12619671 | — |
| Reactant | HCID 53791003 | HCID 53791003 | — |
| Reactant | HCID 54460088 | HCID 54460088 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 54523481 | HCID 54523481 | — |
Reaction Steps
This compound was prepared in accordance with Example 1 using 6.9 g of the hydrochloride of pentyl 3-aminopropanoate, 5.5 g of 2-(2,3-epoxypropoxy)benzonitrile and 1.8 g of NaOH. The crude oil was treated with ether and butyl N-[3-(2-cyanophenoxy)-2-hydroxypropyl]-3-aminopropanoate crystallized. Yield 1.3 g. Melting point 91° C. (HCl). The structure was determined using NMR and equivalent weight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05051446 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-8665bdd9e3ff47c79640c8e82efe0a42 |
| Source note | uspto-grants-1991_09 |