Sodium Hydroxide → HCID 14800668, compound

Participants

Reaction Steps

Methyl 3-(4-(2-quinolinylmethyloxy)benzyl)benzoate (0.05 mol) is heated at reflux in a 9:1 mixture of ethanol and 0.5 N aqueous NaOH (450 ml). After several hours the clear reaction is evaporated. The solid residue is takenup in water and acidified. The resulting crystalline product is isolated byfiltration and dried by suction with a rubber dam to obtain 3-(4-(2-quinolinylmethyloxy)benzyl)benzoic acid.

Provenance & Evidence