HCID 54073919, compound → HCID 14995015, compound

HRID 729036Notes

Reaction equation

HRID 729036 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][O:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][C:21]([C:23]2[CH:28]=[CH:27][C:26]([OH:29])=[CH:25][CH:24]=2)=O)[CH:16]=[CH:17][CH:18]=1.[H][H]>C(OCC)(=O)C.[Pd]>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][O:12][C:13]1[CH:14]=[C:15]([CH2:19][CH2:20][CH2:21][C:23]2[CH:28]=[CH:27][C:26]([OH:29])=[CH:25][CH:24]=2)[CH:16]=[CH:17][CH:18]=1

Participants

5

Reactant 2

HCID 54073919HCID 54073919, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 14995015HCID 14995015, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A solution of 4-(3-(3-(2-quinolinylmethyloxy)phenyl)-1-oxo-2-propen-1-yl)phenol (0.008 mol) in ethyl acetate (150 ml) is shaken under 50 psi of hydrogen gas in the presence of 10% palladium on carbon catalyst (1.0 g). The reaction mixture is filtered through a celite pad and evaporated to give 4-(3(3-(2-quinolinylmethyloxy)phenyl)propyl)phenol.

Workup

  1. filtrationThe reaction mixture is filtered through a celite pad
  2. customevaporated

Sources & evidence

ORD record
ord-3bb0f5d645a14ff1b29087854932fd7b
Source dataset
uspto-grants-1991_09
Patent number
US05051427

Reaction notes

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