1-Octanol → HCID 86623588, compound

HRID 729043Notes

Reaction equation

HRID 729043 reaction equation
[CH2:1]([OH:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]>O>[CH2:1]([OH:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[OH2:9]

Participants

3

Reactant 1

HCID 9571-Octanol

Product 1

HCID 86623588HCID 86623588, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The n-octanol/water partition coefficients were obtained from measurements of the distribution of 1, 3, 5 and 6 umol quantities of each 14C-labeled compound into a mixture of 5 ml of n-octanol and 5 ml water. At each concentration, the amount of labeled compound in the aqueous and n-octanol phases was calculated from the amount of radioactive material present after stirring for 18 hours. A plot of the amount in the n-octanolversus that in the aqueous phase gave a straight line with a slope of K, the partition coefficient. ##EQU3##where A the molar concentration of the compounds.

Workup

  1. customThe n-octanol/water partition coefficients
  2. customwere obtained from measurements of the distribution of 1, 3, 5 and 6 umol quantities of each 14C-
  3. concentrationAt each concentration
  4. customA plot of the amount in the n-octanolversus that in the aqueous phase gave a straight line with a slope of K
  5. concentration##EQU3##where A the molar concentration of the compounds

Sources & evidence

ORD record
ord-33c11ab462ee45f0aaf7da1c96278758
Source dataset
uspto-grants-1991_09
Patent number
US05051448

Reaction notes

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