1-Octanol → HCID 86623588, compound

Participants

Reaction Steps

The n-octanol/water partition coefficients were obtained from measurements of the distribution of 1, 3, 5 and 6 umol quantities of each 14C-labeled compound into a mixture of 5 ml of n-octanol and 5 ml water. At each concentration, the amount of labeled compound in the aqueous and n-octanol phases was calculated from the amount of radioactive material present after stirring for 18 hours. A plot of the amount in the n-octanolversus that in the aqueous phase gave a straight line with a slope of K, the partition coefficient. ##EQU3##where A the molar concentration of the compounds.

Provenance & Evidence