HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 15749830, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 1-(2-Methylphenyl)-4-chloro-6-methylpyrrolo[3,2-c]quinoline | HCID 15749829 | — |
| Product | HCID 15749830 | HCID 15749830 | — |
Reaction Steps
1-(2-Methylphenyl)-4-chloro-6-methylpyrrolo[3,2-c]quinoline (1.5 g, 4.9 mmol) and methylamine (33% in ethanol, 50 ml) were heated to 150° C. in a pressure vessel for 16 hours, then the solvent evaporated. Chromatography (silica gel, 2% methanolic ammonia in dichloromethane) and recrystallisation from aqueous ethanol yielded 1-(2-methylphenyl)-4-methylamino-6-methylpyrrolo[3,2-c]quinoline (0.62 g),m.p. 129°-130°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05051508 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-d80577440c44419fa01be13b384caa64 |
| Source note | uspto-grants-1991_09 |