Benzenamine, 4-(4-morpholinyl)- → 2-Ethyl-4-[(4-morpholin-4-ylphenyl)amino]-5-[4-(trifluoromethyl)phenyl]isothiazol-3(2H)-one 1,1-dioxide

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Reaction Steps

The title compound was prepared from 4-chloro-2-ethyl-5-[4-(trifluoromethyl)phenyl]isothiazol-3(2H)-one 1,1-dioxide and 4-morpholin-4-ylaniline in a similar manner as described for Example 11. 1H NMR (500 MHz, CDCl3): δ 1.51 (t, 3H), 2.98-3.01 (m, 4H), 3.81-3.83 (m, 4H), 3.88 (q, 2H), 6.52 (d, 2H), 6.64 (d, 2H), 7.22 (d, 2H), 7.36 (d, 2H).

Provenance & Evidence