Hydrochloric Acid → HCID 24864087, compound

Participants

Reaction Steps

To a solution of ethyl (5-{5-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]pyrazin-2-yl}-1H-tetrazol-1-yl)acetate (Isomer A) from Step 7 (0.067 g, 0,132 mmol) in THF (2 mL) and MeOH (2 mL) was added 1 N NaOH (2 mL). After approximately 2 h, ethyl acetate and 1 N HCl were added to the reaction mixture. The organic phase was separated, dried over sodium sulfate and evaporated to give the title compound.

Provenance & Evidence