HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → (5-{2-[4-(5-Bromo-2-fluorophenoxy)piperidin-1-yl]pyrimidin-5-yl}-2H-tetrazol-2-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl (5-{2-[4-(5-bromo-2-fluorophenoxy)piperidin-1-yl]pyrimidin-5-yl}-2H-tetrazol-2-yl)acetate | HCID 86621805 | — |
| Product | (5-{2-[4-(5-Bromo-2-fluorophenoxy)piperidin-1-yl]pyrimidin-5-yl}-2H-tetrazol-2-yl)acetic acid | HCID 57832727 | — |
Reaction Steps
The title compound was prepared in a similar manner as that described for Example 3 (step 5) from ethyl (5-{2-[4-(5-bromo-2-fluorophenoxy)piperidin-1-yl]pyrimidin-5-yl}-2H-tetrazol-2-yl)acetate and aqueous NaOH.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582633B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-f99d5fe714fe43d599c49f0f5634cb2c |
| Source note | uspto-grants-2009_09 |