HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Bromomethyl)-3-chloro-2-fluorobenzene → 2-[(3-Chloro-2-fluorobenzyl)thio]-4,6-pyrimidinediol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Bromomethyl)-3-chloro-2-fluorobenzene | HCID 522827 | — |
| Reactant | HCID 178516656 | HCID 178516656 | — |
| Product | 2-[(3-Chloro-2-fluorobenzyl)thio]-4,6-pyrimidinediol | HCID 178516653 | — |
Reaction Steps
The subtitle compound was prepared by the method of Example 19 step i) using 2-mercaptopyrimidine-4,6-diol (20.0 g) and 3-chloro-2-fluorobenzyl bromide to afford the subtitle compound as a white solid. Yield: 36.2 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582644B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-69cb2091ecd14235b8134ff3d876cfdc |
| Source note | uspto-grants-2009_09 |