反应详情

温度

20 °C

A stirred solution of 4-iodomethyltetrahydropyran (3.43 g, 15.2 mmol) and PPh3 (3.98 g, 15.2 mmol) in anhydrous MeCN (10 mL) was heated under reflux for 19 h. On cooling to 20° C., Et2O (50 mL) was added. The precipitate formed was collected, washed with Et2O (150 mL), and recrystallised (MeCN) to give the title compound: m/z (ES+)=361.2 [M]+.

1. temperatureunder reflux for 19 h
2. customThe precipitate formed
3. customwas collected
4. washwashed with Et2O (150 mL)
5. customrecrystallised (MeCN)