HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine hydrochloride → HCID 58860834, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine hydrochloride | HCID 6364545 | — |
| Reactant | HCID 21093936 | HCID 21093936 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 58860834 | HCID 58860834 | — |
Reaction Steps
2-[2-(4-Methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)propionylamino]thiazole-5-carboxylic acid (EXAMPLE 127, 399 mg, 0.91 mmol) was condensed with MeNH2.HCl in the presence of NEt3, utilising the general procedure described in EXAMPLE 65, to give the title compound: RTA=2.82 min; m/z (ES+)=452.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582632B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-977d900e65a04a4aa18c652f7f5400e7 |
| Source note | uspto-grants-2009_09 |