4-Aminophenol → HCID 23023075, compound
Reaction equation
N[C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][CH:17]=1)[O:5][C:6]1[CH:11]=[CH:10][N:9]=[C:8]([C:12](N)=O)[CH:7]=1.[NH2:18]C1C=CC(O)=CC=1.ClC1C=CN=C(C)C=1>>[CH3:12][C:8]1[CH:7]=[C:6]([O:5][C:4]2[CH:3]=[CH:2][C:17]([NH2:18])=[CH:16][CH:15]=2)[CH:11]=[CH:10][N:9]=1Participants
4
Procedure
{4-[(2-Methylpyridin-4-yl)oxy)phenyl}amine (2B) was prepared by a method analogous to that described for 4-(3-aminophenoxy)pyridine-2-carboxamide (2C), starting from 4-aminophenol and 4-chloro-2-methylpyridine, MS ES: 201 (M+H)+, calcd 201, RT=1.01 min.
Sources & evidence
- ORD record
- ord-7c574cffbbc44accbd267f43bd64022a
- Source dataset
- uspto-grants-2009_09
- Patent number
- US07582645B2
Reaction notes
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