Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 729940Generated: October 26, 2026

4-Chloro-2-pyridinecarbonitrile → 4-[4-Amino-3-(trifluoromethyl)phenoxy]pyridine-2-carbonitrile

https://huagongshe.com/reaction/729940

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-2-pyridinecarbonitrileHCID 693342—
Reactant2-Amino-5-hydroxybenzotrifluorideHCID 14692834—
Reactant4-(3-Aminophenoxy)pyridine-2-carboxamideHCID 23137229—
Product4-[4-Amino-3-(trifluoromethyl)phenoxy]pyridine-2-carbonitrileHCID 57833441—

Reaction Steps

This material is prepared by a method analogous to that described for preparation of 2C, starting from 4-amino-3-(trifluoromethyl) phenol and 4-chloro-2-cyanopyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582646B2
Source datasetuspto-grants-2009_09
ORD IDord-b58e1343a7304e60af40ad249e5e5f1e
Source noteuspto-grants-2009_09