Trifluoroacetate → Trifluoroacetic acid

HRID 730080Notes

Reaction equation

HRID 730080 reaction equation
[CH:1]12[NH:8][CH:5]([CH2:6][CH2:7]1)[CH2:4][C:3](=[C:9]1[C:22]3[CH:21]=[CH:20][CH:19]=[C:18]([C:23]([NH2:25])=[O:24])[C:17]=3[O:16][C:15]3[C:10]1=[CH:11][CH:12]=[CH:13][CH:14]=3)[CH2:2]2.[F:26][C:27]([F:32])([F:31])[C:28]([O-:30])=[O:29].C12NC(CC1)CC(=[C:41]1[C:54]3[CH:53]=CC=C(O)[C:49]=3[O:48][C:47]3C1=CC=CC=3)C2>>[O:48]1[CH:47]=[CH:41][C:54]([CH2:53][N:8]2[CH:1]3[CH2:7][CH2:6][CH:5]2[CH2:4][C:3](=[C:9]2[C:22]4[CH:21]=[CH:20][CH:19]=[C:18]([C:23]([NH2:25])=[O:24])[C:17]=4[O:16][C:15]4[C:10]2=[CH:11][CH:12]=[CH:13][CH:14]=4)[CH2:2]3)=[CH:49]1.[C:28]([OH:30])([C:27]([F:32])([F:31])[F:26])=[O:29]

Participants

5

Reactant 3

HCID 84468TrifluoroacetateHCID 15986280HCID 15986280, compoundHCID 15986281HCID 15986281, compound

Product 2

HCID 6422Trifluoroacetic acidHCID 15986282HCID 15986282, compound

Procedure

Using an adaptation of the method described in Procedure 6, substituting 9-(8-azabicyclo[3.2.1 ]oct-3-ylidene)-9H-xanthene-4-carboxylic acid amide for the trifluoroacetate salt of compound 2, the title compound 4 was obtained as a TFA salt.

Sources & evidence

ORD record
ord-94dbb4dced1144b68d56589d0efac326
Source dataset
uspto-grants-2009_09
Patent number
US07582650B2

Reaction notes

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