Aniline → HCID 15986359, compound

HRID 730088Notes

Reaction equation

HRID 730088 reaction equation
O=[C:2]1[C:15]2[CH:14]=[CH:13][CH:12]=[C:11]([C:16](O)=[O:17])[C:10]=2[O:9][C:8]2[C:3]1=[CH:4][CH:5]=[CH:6][CH:7]=2.[NH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[OH-].[NH4+:27]>>[C:20]1([NH:19][C:16]([C:11]2[C:10]3[O:9][C:8]4[C:7](=[CH:15][CH:2]=[CH:3][CH:4]=4)[C:2](=[C:3]4[CH2:7][CH:6]5[NH:27][CH:5]([CH2:6][CH2:5]5)[CH2:4]4)[C:15]=3[CH:14]=[CH:13][CH:12]=2)=[O:17])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

4

Reactant 3

HCID 6115AnilineHCID 14923Ammonium HydroxideHCID 410100HCID 410100, compound

Product 1

HCID 15986359HCID 15986359, compound

Procedure

Using an adaptation of the method described in Procedures 25 and 33, substituting 3-(4-carboxyxanthen-9-ylidene)-8-azabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester 2m for 9-oxo-9H-xanthene-4-carboxylic acid 5j and aniline for ammonium hydroxide in Procedure 25, the title compound 12 was obtained.

Sources & evidence

ORD record
ord-57f698f483e54a96946debf1f5c2c029
Source dataset
uspto-grants-2009_09
Patent number
US07582650B2

Reaction notes

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