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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 730552Generated: October 28, 2026

Indole → 3-Bromo-1h-indole

https://huagongshe.com/reaction/730552

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndoleHCID 798—
ReactantN-bromobutanimideHCID 67184—
Product3-Bromo-1h-indoleHCID 2763277—

Reaction Steps

In step 3 indole compound k undergoes bromination by treatment with N-bromosuccinimide or other bromime source (not shown) to yield 3-bromo indole compound l. Bromoindole l is then subject to oxidation in step 4 to provide dihydroindolone compound m. Compound m is a compound of formula I in accordance with the invention.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582760B2
Source datasetuspto-grants-2009_09
ORD IDord-1537cf4be3484571bd51d70d51c62c2d
Source noteuspto-grants-2009_09