Diethyl Ether → HCID 68817750, compound

Participants

Reaction Steps

[2-(1-Benzyl-2-oxo-2,3-dihydro-1H-benzoimidazol-4-yl)-ethyl]-methyl-carbamic acid tert-butyl ester (31 mg) was dissolved in 2.0 ml of tetrahydrofuran and 100 uL of 2.0 N HCl/EtOH was added. The solution was heated on a steam bath for 30 minutes and then after cooling diethyl ether was slowly added to produce 10 mg of 1-benzyl-4-(2-methylamino-ethyl)-1,3-dihydro-benzoimidazol-2-one hydrochloride salt as a colorless powder. MS: 282 (M+H)−.

Provenance & Evidence