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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 730579Generated: October 29, 2026

Phosphoric Acid → [2-(1-benzyl-2-oxo-2,3-dihydro-1H-indol-4-yloxy)-ethyl]-methyl-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/730579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphoric AcidHCID 1004—
Reactant[2-(1-benzyl-3-bromo-1H-indol-4-yloxy)-ethyl]-methyl-carbamic acid tert-butyl esterHCID 57834989—
Product[2-(1-benzyl-2-oxo-2,3-dihydro-1H-indol-4-yloxy)-ethyl]-methyl-carbamic acid tert-butyl esterHCID 57834977—

Reaction Steps

[2-(1-Benzyl-3-bromo-1H-indol-4-yloxy)-ethyl]-methyl-carbamic acid tert-butyl ester was treated with phosphoric acid using the procedure of step 4 of Example 6 to provide [2-(1-benzyl-2-oxo-2,3-dihydro-1H-indol-4-yloxy)-ethyl]-methyl-carbamic acid tert-butyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582760B2
Source datasetuspto-grants-2009_09
ORD IDord-7d94f7e9a75440b6b0b9e45363fd6539
Source noteuspto-grants-2009_09