Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 730755Generated: October 26, 2026

4-bromo-2-chloro-6-trifluoromethyl-1H-benzoimidazole → HCID 178519686, compound

https://huagongshe.com/reaction/730755

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-bromo-2-chloro-6-trifluoromethyl-1H-benzoimidazoleHCID 11594585—
Reactant2-(1-piperazinyl)-3-PyridinemethanolHCID 67400406—
ProductHCID 178519686HCID 178519686—

Reaction Steps

(2-Piperazin-1-ylpyridin-3-yl)methanol (0.48 g, 2.5 mmol, Example 46a) reacted with 4-bromo-2-chloro-6-trifluoromethyl-1H-benzoimidazole (0.60 g, 2 mmol, Example 6b) under the conditions of Example 3c to give the title compound as a white amorphous solid. MS (ESI, pos. ion) m/z: 456 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582761B2
Source datasetuspto-grants-2009_09
ORD IDord-48c8977adccb4edbba00350590e427d3
Source noteuspto-grants-2009_09