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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 730758Generated: October 25, 2026

2,3-Dichloropyridine → HCID 178461514, compound

https://huagongshe.com/reaction/730758

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DichloropyridineHCID 16988—
ReactantDiisopropylethylamineHCID 81531—
ReactantHCID 178461512HCID 178461512—
ProductHCID 178461514HCID 178461514—

Reaction Steps

A mixture of 2,3-dichloro-pyridine (44 mg, 0.3 mmol, Aldrich), 7-chloro-2-[(3R)-3-methylpiperazin-1-yl]-5-(trifluoromethyl)-1H-benzoimidazole (80 mg, 0.25 mmol, Example 48a) and N,N-diisopropylethylamine (0.1 mL, 0.58 mmol, Aldrich) reacted under the conditions of Example 48b to give the title compound as a white amorphous solid. MS (ESI, pos. ion) m/z: 430 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582761B2
Source datasetuspto-grants-2009_09
ORD IDord-7d79c8bd2b5b43e48ed12fe63647c95e
Source noteuspto-grants-2009_09