反应详情

To a solution of ethyl 2-ethyl-2H-indazole-5-carboxylate (step-1 of Example 13, 150 mg, 0.69 mmol) in THF (10 mL) was added LiAlH4 (26 mg, 0.69 mmol) at 0° C. The mixture was stirred at room temperature for 1 hr. The mixture was quenched with saturated aqueous NH4Cl. The precipitate was filtered off. The filtrate was concentrated to give the titled compound (131 mg, quant) as an orange colored oil.

1. customThe mixture was quenched with saturated aqueous NH4Cl
2. filtrationThe precipitate was filtered off
3. concentrationThe filtrate was concentrated