3-Bromo-2-chloropyridine → HCID 11658915, compound

HRID 730779Notes

Reaction equation

HRID 730779 reaction equation
[Br:1][C:2]1[C:3](Cl)=[N:4][CH:5]=[CH:6][CH:7]=1.[CH3:9][C@H:10]1[CH2:15][NH:14][CH2:13][CH2:12][NH:11]1>>[Br:1][C:2]1[C:3]([N:14]2[CH2:13][CH2:12][NH:11][C@@H:10]([CH3:9])[CH2:15]2)=[N:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 6933243-Bromo-2-chloropyridineHCID 27342192-Methylpiperazine, (S)-

Product 1

HCID 11658915HCID 11658915, compound

Procedure

A mixture of 3-bromo-2-chloropyridine (0.76 g, 4 mmol, Aldrich) and (S)-(+)-2-methylpiperazine (0.6 g. 6 mmol, Aldrich) reacted under the conditions of Example 3c to give the title compound as a light-brown solid. MS (ESI, pos. ion) m/z: 256 (M+1).

Workup

  1. customreacted under the conditions of Example 3c

Sources & evidence

ORD record
ord-200da2a6c6b4488fa297063ac4f27bd5
Source dataset
uspto-grants-2009_09
Patent number
US07582761B2

Reaction notes

Loading…