HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-bromo-2-chloro-6-trifluoromethyl-1H-benzoimidazole → HCID 178461521, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-bromo-2-chloro-6-trifluoromethyl-1H-benzoimidazole | HCID 11594585 | — |
| Reactant | (R)-1-(3-chloropyridin-2-yl)-3-methylpiperazine | HCID 11658551 | — |
| Product | HCID 178461521 | HCID 178461521 | — |
Reaction Steps
4-Bromo-2-chloro-6-trifluoromethyl-1H-benzoimidazole (1.2 g, 4 mmol, Example 6b) reacted with (3R)-1-(3-chloropyridin-2-yl)-3-methylpiperazine (0.95 g, 4.5 mmol, Example 74a) under the conditions of Example 3c to give the title compound as a light-yellow solid. MS (ESI, pos. ion) m/z: 474 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582761B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-73f472efc2a9467b98680d5e38200745 |
| Source note | uspto-grants-2009_09 |