Acetic Anhydride → N-[4-Bromo-3-(trifluoromethyl)phenyl]acetamide

Participants

Reaction Steps

A mixture of 4-bromo-3-(trifluoromethyl)phenylamine (7.2 g, 30 mmol, Aldrich) and acetic anhydride (29 mL) was stirred at room temperature for 16 h. The reaction mixture was evaporated in vacuo to give the title product as a white solid which was used in the next step without additional purification. MS (ESI, pos. ion) m/z: 484.0 (M+1).

Provenance & Evidence