HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-6-(trifluoromethyl)-1H-benzimidazole → HCID 178461528, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-6-(trifluoromethyl)-1H-benzimidazole | HCID 337905 | — |
| Reactant | 2-[5-Chloro-6-[(3R)-3-methyl-piperazin-1-yl]-pyridin-3-yl]-propan-2-ol | HCID 67400439 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178461528 | HCID 178461528 | — |
Reaction Steps
A mixture of 2-chloro-6-trifluoromethyl-1H-benzoimidazole (58 mg, 0.26 mmol, Example 1c) and 2-[5-chloro-6-[(3R)-3-methyl-piperazin-1-yl]-pyridin-3-yl]-propan-2-ol from step (c) above (90 mg, 0.33 mmol) in ethanol (1 mL) reacted under the conditions of Example 3c to give the title compound. MS (ESI, pos. ion) m/z: 454 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582761B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-38f58c2c3d0d4d2e828ebdd001d5cdd3 |
| Source note | uspto-grants-2009_09 |